The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 10, 2002
Filed:
Aug. 28, 2000
Applicant:
Inventors:
Ezra S. Abrams, W. Newton, MA (US);
Tianhong Zhang, Framingham, MA (US);
Slawomir Mielewczyk, Newton, MA (US);
Brian C. Patterson, Waltham, MA (US);
Assignee:
Matrix Technologies Corporation, Hudson, NH (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12M 1/36 ; C12N 1/116 ; C07H 2/104 ; C07K 5/00 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12M 1/36 ; C12N 1/116 ; C07H 2/104 ; C07K 5/00 ;
Abstract
A method is provided for immobilizing a ligand, e.g., a nucleic acid, on a solid support. The method includes providing a solid support containing an immobilized latent thiol group, activating the thiol group, contacting the activated thiol group with a nucleic acid comprising an acrylamide functional group, and forming a covalent bond between the two groups, thereby immobilizing the nucleic acid to the solid support. Kits containing the solid supports and method of utilizing the solid supports are also provided.