This inventor holds 41 USPTO granted patents and 28 published patent applications and 5 EPO patents, primarily in Hematopoietic Stem Cells. Top assignees: The General Hospital Corporation, Harvard College, Children's Medical Center Corporation. Active years: 1997-2026.
Location History:
- South San Fran, CA (US) (2000)
- Weston, MA (US) (1997 - 2023)
- Boston, MA (US) (2021 - 2023)
Company Filing History:
30 out of 3,068Â 
13 out of 3,069Â 
4 out of 1,072Â 
Years Active: 1997-2026
Areas of Expertise:
Title: **David T. Scadden: Innovations in Immunotherapy and Stem Cell Research**
Introduction
David T. Scadden is a prominent inventor based in Weston, MA, known for his significant contributions to the fields of immunotherapy and stem cell research. With an impressive portfolio of 39 patents to his name, Scadden has been instrumental in developing novel therapeutic approaches that enhance treatment options for various diseases.
Latest Patents
Among Scadden's latest innovative patents are two noteworthy inventions. The first, titled "Monocyte compositions and methods for the treatment of infectious disease," focuses on compositions that comprise subsets of monocytes with distinct functional properties. This invention aims to utilize these specialized cells in treating infectious diseases effectively.
The second patent, "Compositions and methods for non-myeloablative conditioning," reveals non-myeloablative antibody-toxin conjugates that target specific cell surface markers, such as CD34, CD45, or CD117. This invention provides methods for conditioning a subject's tissues, particularly bone marrow, prior to engraftment or transplant. Importantly, these methods minimize the toxicities often associated with traditional conditioning practices, making them a valuable advancement in medical treatments, particularly for hematopoietic stem cell transplants.
Career Highlights
Scadden's career has seen him associated with esteemed institutions such as The General Hospital Corporation and the President and Fellows of Harvard College. His work at these institutions has paved the way for remarkable advancements in medical science, particularly in the realms of stem cell biology and regenerative medicine.
Collaborations
David Scadden has collaborated with notable peers, including Mark C. Poznansky and Laura Maria Calvi, contributing to a rich environment of innovation and research. These collaborations have enhanced the development and application of his patented inventions, furthering the impact of his work in medical research.
Conclusion
David T. Scadden continues to be a significant force in the field of biomedical innovation. His patents reflect a dedication to improving therapeutic options for patients, showcasing the potential of targeted cellular therapies in treating complex diseases. As a seasoned inventor, Scadden's work exemplifies the transformative power of innovation in medicine.