The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2014
Filed:
Nov. 02, 2012
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
David T. Scadden, Weston, MA (US);
Laura M. Calvi, Rochester, NY (US);
Gregor Adams, South Pasadena, CA (US);
Henry M. Kronenberg, Belmont, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 35/26 (2006.01); C12N 5/00 (2006.01); A61K 35/28 (2006.01); C12Q 1/68 (2006.01); C12N 5/0789 (2010.01); C12N 5/0775 (2010.01); C12N 5/071 (2010.01); C07K 14/72 (2006.01); G01N 33/74 (2006.01); A61K 38/29 (2006.01); C12N 5/0797 (2010.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0602 (2013.01); A61K 35/28 (2013.01); C12Q 1/6809 (2013.01); A01K 2227/105 (2013.01); C12N 5/0647 (2013.01); C12N 5/0675 (2013.01); C12N 2501/37 (2013.01); C12N 2502/1311 (2013.01); C12N 2502/1394 (2013.01); C07K 14/72 (2013.01); G01N 33/74 (2013.01); A61K 38/29 (2013.01); C12N 5/0623 (2013.01); A01K 2217/05 (2013.01); A61K 38/17 (2013.01);
Abstract
The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells.