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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11096934 B1

PDFFull Text
Date of Patent:
Aug. 24, 2021

Filed:

Aug. 29, 2016

Compounds and methods useful for treating or preventing hematological cancers

Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

The General Hospital Corporation, Boston, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Bayer Pharma Aktiengesellschaft, Berlin, DE;

Inventors:

David B. Sykes, Boston, MA (US);

David Scadden, Boston, MA (US);

Timothy A. Lewis, Cambridge, MA (US);

Andreas Janzer, Berlin, DE;

Hanna Meyer, Berlin, DE;

Detlef Stöckigt, Potsdam, DE;

Assignees:

THE BROAD INSTITUTE, INC., Cambridge, MA (US);

THE GENERAL HOSPITAL CORPORATION, Boston, MA (US);

PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US);

BAYER PHARMA AKTIENGESELLSCHAFT, Berlin, DE;

Attorneys:

Greenberg Traurig, LLP

Melissa Hunter-Ensor

Scott Goncher

Primary Examiner:

David J Blanchard

Assistant Examiner:

Ivan A Greene

Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61P 35/02 (2006.01); A61K 31/277 (2006.01); A61K 33/36 (2006.01); A61K 31/42 (2006.01); A61K 31/505 (2006.01); A61K 31/27 (2006.01);
U.S. Cl.
CPC ...
A61K 31/47 (2013.01); A61K 31/27 (2013.01); A61K 31/277 (2013.01); A61K 31/42 (2013.01); A61K 31/505 (2013.01); A61K 33/36 (2013.01); A61P 35/02 (2018.01);
Abstract

The present invention includes methods of treating patients with acute myeloid leukemia across a range of genetic subtypes with DHODH inhibitors, such as 6-fluoro-2-(2'-fluoro-[1,1′-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid).

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Sykes, David. (2021). Compounds and methods useful for treating or preventing hematological cancers (U.S. Patent No. 11096934). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11096934

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