Colleen T O'Loughlin

Title: Innovations by Colleen T O'Loughlin

Introduction

Colleen T O'Loughlin is a prominent inventor based in Princeton, NJ (US). She has made significant contributions to the field of antimicrobial research, focusing on innovative strategies to combat gram-negative bacteria. With a total of 5 patents, her work has garnered attention for its potential applications in medical and environmental settings.

Latest Patents

O'Loughlin's latest patents include groundbreaking molecules and compositions that inhibit gram-negative bacteria and their uses. One of her strategies involves the synthesis of a series of compounds that inhibit the production of pyocyanin, a virulence factor produced by this pathogen. Additionally, she has developed compounds that inhibit the two quorum-sensing receptors, LasR and RhlR, which play a crucial role in biofilm formation and virulence. Another notable patent features a novel small molecule that antagonizes two types of acyl homoserine lactone receptors, providing a protective mechanism against quorum-sensing-mediated killing by bacterial pathogens.

Career Highlights

Colleen T O'Loughlin is affiliated with Princeton University, where she conducts her research and develops her innovative solutions. Her work has not only advanced scientific understanding but also opened new avenues for antimicrobial therapies.

Collaborations

O'Loughlin collaborates with esteemed colleagues such as Bonnie L Bassler and Lee R Swem, contributing to a rich environment of innovation and discovery.

Conclusion

Colleen T O'Loughlin's contributions to antimicrobial research exemplify the impact of innovative thinking in addressing critical health challenges. Her patents reflect a commitment to advancing science and improving public health outcomes.