The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2017
Filed:
Sep. 19, 2014
The Trustees of Princeton University, Princeton, NJ (US);
Bonnie L. Bassler, Princeton, NJ (US);
Martin F. Semmelhack, Princeton, NJ (US);
Knut Drescher, Princeton, NJ (US);
Albert Siryaporn, Princeton Junction, NJ (US);
Laura C. Miller, Princeton, NJ (US);
Colleen T. O'loughlin, San Francisco, CA (US);
Bonnie L. Bassler, Princeton, NJ (US);
Martin F. Semmelhack, Princeton, NJ (US);
Knut Drescher, Princeton, NJ (US);
Albert Siryaporn, Princeton Junction, NJ (US);
Laura C. Conrad-Miller, Princeton, NJ (US);
Colleen T. O'Loughlin, San Francisco, CA (US);
THE TRUSTEES OF PRINCETON UNIVERSITY, Princeton, NJ (US);
Abstract
Antivirulence strategies to combat, are described. One strategy encompasses synthesis of a series of compounds that inhibit the production of pyocyanin, a redox-active virulence factor produced by this pathogen. A related strategy encompasses synthesis of compounds that inhibit the twoquorum-sensing receptors, LasR and RhlR, inhibit production of pyocyanin, and inhibit biofilm formation.