Concord, MA, United States of America

Braydon Charles Guild

This inventor holds 61 USPTO granted patents and 32 published patent applications, plus 9 CIPO patents and 21 EPO patents, primarily in Lipid Nanoparticle Delivery (CPC class A61K). Top assignees: Translate Bio, Inc., Ethris Gmbh, Shire Human Genetic Therapies, Inc.. Active years: 1997-2026.

USPTO Granted Patents = 61 

% Patents Active = 98.4

 

 

Average Co-Inventor Count = 3.4

ph-index = 15

Forward Citations = 991(Granted Patents)

Forward Citations (Not Self Cited) = 738(Dec 10, 2025)


Inventors with similar research interests:


Location History:

  • Concord, MA (US) (1997 - 2022)
  • Lexington, MA (US) (2019 - 2024)
  • Cambridge, MA (US) (2024)

Company Filing History:


Years Active: 1997-2026

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Areas of Expertise:
mRNA Compositions
Lipid Nanoparticles
Cationic Lipids
Nucleic Acid Delivery
Cleavable Lipids
Antibody Delivery
Genetic Disease Treatment
Pulmonary Delivery
Blended Formulations
Neutral Nanoparticles
Synergistic Enhancement
Nuclease Resistant Polynucleotides
61 patents (USPTO):Explore Patents

Title: Braydon Charles Guild: Innovating mRNA Delivery Solutions

Introduction

Braydon Charles Guild is a prominent inventor based in Concord, MA, known for his significant contributions to the field of biotechnology. With an impressive portfolio of 55 patents, Guild has been pivotal in developing innovative solutions for mRNA delivery and lipid nanoparticle compositions that have the potential to revolutionize therapeutic approaches.

Latest Patents

Among his latest patents, Guild has developed lipid nanoparticle compositions and methods for mRNA delivery, which focus on modulating protein production in target cells. These innovative compositions aim to treat diseases associated with protein or enzyme deficiencies. Additionally, his patent on cleavable lipids introduces novel compounds that serve as liposomal delivery vehicles, facilitating the targeted delivery of encapsulated polynucleotides. These compounds are characterized by advantageous properties compared to other similar lipids, underscoring their potential in enhancing transfection efficiencies in target cells.

Career Highlights

Guild has enjoyed a successful career as an inventor and researcher, having worked with renowned companies such as Translate Bio, Inc. and Shire Human Genetic Therapies, Inc. His expertise in biotechnology and passion for innovation have contributed to his prolific output of patents, establishing him as a leader in his field.

Collaborations

Throughout his career, Braydon has collaborated with various professionals, including noteworthy coworkers like Michael W Heartlein and Frank DeRosa. These collaborations have facilitated the exchange of ideas and fostered advancements in the development of cutting-edge biotechnological solutions.

Conclusion

Braydon Charles Guild stands out as a visionary inventor whose work continues to push the boundaries of biotechnology. With his latest patents focusing on mRNA delivery and lipid nanoparticle technology, Guild’s innovations promise to open new avenues for treating complex diseases, highlighting the importance of ongoing research and development in this critical field.

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