The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 04, 2024
Filed:
Aug. 03, 2020
Applicant:
Translate Bio, Inc., Lexington, MA (US);
Inventors:
Frank DeRosa, Lexington, MA (US);
Braydon Charles Guild, Lexington, MA (US);
Michael Heartlein, Lexington, MA (US);
Assignee:
TRANSLATE BIO, INC., Waltham, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01); A61K 9/127 (2006.01); A61K 9/50 (2006.01); A61K 38/18 (2006.01); A61K 38/47 (2006.01); A61K 48/00 (2006.01); C07C 211/21 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07C 211/21 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 9/5015 (2013.01); A61K 38/1816 (2013.01); A61K 38/47 (2013.01); C12N 15/85 (2013.01); C12Y 302/01023 (2013.01);
Abstract
Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent transfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids.