The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2025
Filed:
Mar. 31, 2020
Applicant:
Translate Bio, Inc., Lexington, MA (US);
Inventors:
Frank Derosa, Lexington, MA (US);
Lianne Smith, Lexington, MA (US);
Michael Heartlein, Lexington, MA (US);
Braydon Charles Guild, Lexington, MA (US);
Assignee:
TRANSLATE BIO, INC., Waltham, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7105 (2006.01); A61K 9/00 (2006.01); A61K 9/1271 (2025.01); A61K 9/1272 (2025.01); A61K 9/14 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 9/145 (2013.01); A61K 9/146 (2013.01); A61K 48/0025 (2013.01); A61K 48/0033 (2013.01); A61K 9/0019 (2013.01); A61K 9/0085 (2013.01);
Abstract
Disclosed herein are pharmaceutical compositions that comprise 'blends' of lipid nanoparticles and related methods of using such blended compositions to deliver polynucleotides to one or more target cells, tissues or organs. The blended compositions are generally characterized as being able to efficiently deliver polynucleotides to target cells and by their ability to enhance the expression of such polynucleotides and the production of functional proteins by target cells.