logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12102720 B1

PDFFull Text
Date of Patent:
Oct. 01, 2024

Filed:

Dec. 20, 2021

Cleavable lipids

Applicant:

Translate Bio, Inc., Lexington, MA (US);

Inventors:

Braydon Charles Guild, Concord, MA (US);

Michael Heartlein, Boxborough, MA (US);

Frank DeRosa, Chelmsford, MA (US);

Jerry Chi Zhang, Lexington, MA (US);

Assignee:

Translate Bio, Inc., Cambridge, MA (US);

Attorney:

McNeill PLLC

Primary Examiner:

D L Jones

Int. Cl.
CPC ...
A61K 9/19 (2006.01); A61K 9/127 (2006.01); A61K 31/7088 (2006.01); A61K 38/45 (2006.01); A61K 38/46 (2006.01); A61K 38/47 (2006.01); A61K 38/50 (2006.01); C07C 323/25 (2006.01); C07C 323/27 (2006.01); C07C 323/44 (2006.01); C07D 233/64 (2006.01); C07J 41/00 (2006.01); C07J 43/00 (2006.01); C12N 15/88 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 9/19 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 31/7088 (2013.01); A61K 38/45 (2013.01); A61K 38/465 (2013.01); A61K 38/47 (2013.01); A61K 38/50 (2013.01); C07C 323/25 (2013.01); C07C 323/27 (2013.01); C07C 323/44 (2013.01); C07D 233/64 (2013.01); C07J 41/0055 (2013.01); C07J 43/003 (2013.01); C12N 15/88 (2013.01); A61K 9/5123 (2013.01); C12Y 201/03003 (2013.01); C12Y 203/01 (2013.01); C12Y 207/08015 (2013.01); C12Y 301/06 (2013.01); C12Y 302/01022 (2013.01); C12Y 302/01035 (2013.01); C12Y 302/01046 (2013.01); C12Y 302/01076 (2013.01); C12Y 305/03001 (2013.01);
Abstract

Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent transfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids.

Find Patent Forward Citations

Guild, Braydon. (2024). Cleavable lipids (U.S. Patent No. 12102720). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12102720

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…