Anne N Murphy

Title: Innovations and Contributions of Anne N Murphy

Introduction

Anne N Murphy is a prominent inventor based in Encinitas, California. She has made significant contributions to the field of biomedical research, particularly in the areas of inflammation and arthritic disorders. With a total of six patents to her name, her work has the potential to impact therapeutic approaches for various diseases.

Latest Patents

Among her latest patents, Anne has developed methods and agents for modulating inflammation. These methods focus on the modulation of intracellular coenzyme A levels for therapeutic purposes. Increasing intracellular coenzyme A can enhance alternate macrophage activation, which may help suppress or resolve immune responses beneficial for treating inflammatory diseases. Conversely, decreasing intracellular coenzyme A levels can reduce alternate macrophage activation, aiding in the treatment of non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), and various fibrotic diseases. Additionally, her work addresses the reversal of immune-suppressing activity of tumor-associated immune cells, such as macrophages, which is crucial for cancer treatment.

Another significant patent involves methods and compositions for diagnosing and treating arthritic disorders and regulating bone mass. This invention relates to improved diagnostic methods for early detection of risks associated with developing arthritic disorders in humans. It includes screening assays for therapeutic agents useful in treating these disorders by comparing levels of indicators of altered mitochondrial function. These indicators encompass various mitochondrial enzymes, ATP biosynthesis factors, and other cellular responses.

Career Highlights

Anne has worked with notable organizations, including Mitokor, Inc. and the University of California. Her experience in these institutions has allowed her to advance her research and contribute to innovative solutions in her field.

Collaborations

Throughout her career, Anne has collaborated with esteemed colleagues such as Robert E Davis and William Christensen Clevenger. These partnerships have further enriched her research endeavors and expanded the impact of her inventions.

Conclusion

Anne N Murphy's innovative work in modulating inflammation and addressing arthritic disorders showcases her dedication to advancing medical science. Her patents reflect a commitment to improving therapeutic strategies for various health conditions.