The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 2004
Filed:
Nov. 03, 2000
Applicant:
Inventors:
Anne N. Murphy, Encinitas, CA (US);
William Clevenger, Oceanside, CA (US);
Sandra Eileen Wiley, San Diego, CA (US);
Alexander Y. Andreyev, San Diego, CA (US);
Luciano G. Frigeri, San Diego, CA (US);
Gonul Velicelebi, San Diego, CA (US);
Robert E. Davis, San Diego, CA (US);
Assignee:
MitoKor, Inc., San Diego, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/00 ; G01N 3/353 ; A01N 4/728 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; C12Q 1/00 ; G01N 3/353 ; A01N 4/728 ; C07H 2/104 ;
Abstract
Compositions and methods are provided for identifying agents that alter mitochondrial membrane permeability transition. The screening methods generally detect agents that alter the interaction between the mitochondrial adenine nucleotide translocator and cyclophilin D. Such agents may be used, for example, in the treatment of a variety of conditions associated with altered mitochondrial function.