Location History:
- Baltimore, MD (US) (1996 - 1999)
- Silver Spring, MD (US) (1997 - 2021)
Company Filing History:
13 out of 192 
10 out of 10 
4 out of 13 
Years Active: 1996-2024
Title: Andrew Lees: Innovator in Recombinant Protein Production
Introduction
Andrew Lees, a prolific inventor based in Silver Spring, MD, has made significant contributions to the field of biotechnology. With an impressive portfolio of 30 patents, Lees exemplifies innovation in the production of recombinant proteins. His work focuses on improving methodologies for producing high levels of soluble recombinant proteins, which are essential for various medical and industrial applications.
Latest Patents
Among his most recent patents, Lees has developed innovative processes for the production of soluble recombinant proteins devoid of N-terminal methionine. His inventions include methods for enzymatically removing the f-met group at the 5'-terminus of recombinant proteins. These processes utilize cells that possess mutations in disulfide reductase genes, resulting in reduced disulfide reductase activity, thereby enhancing the yield of soluble CRM protein. Furthermore, his patents also cover purification methods for CRM as well as the characterization of correctly folded CRM proteins, showcasing his commitment to advancing production techniques in biotechnology.
Career Highlights
Throughout his career, Andrew Lees has been associated with notable organizations that have refined his expertise in the life sciences. He has worked at the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. and Fina Biosolutions, LLC, where he has been instrumental in developing cutting-edge solutions in health care and protein production.
Collaborations
Lees has collaborated with distinguished professionals in his field, including James J. Mond and Richard F. Schuman. These partnerships have undoubtedly enriched his work, promoting a multidisciplinary approach to solving complex challenges in biotechnological research and development.
Conclusion
Andrew Lees continues to be a leading figure in the realm of recombinant protein production. Through his innovations and collaborative efforts, he is paving the way for advancements that could have a far-reaching impact in the medical and scientific community. His extensive patent portfolio is a testament to his dedication to research and development in biotechnology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.