The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 31, 2007
Filed:
Dec. 20, 2002
Jeffrey R. Stinson, Brookeville, MD (US);
Richard F. Schuman, Gaithersburg, MD (US);
James J. Mond, Silver Spring, MD (US);
Andrew Lees, Silver Spring, MD (US);
Gerald Walter Fischer, Bethesda, MD (US);
Jeffrey R. Stinson, Brookeville, MD (US);
Richard F. Schuman, Gaithersburg, MD (US);
James J. Mond, Silver Spring, MD (US);
Andrew Lees, Silver Spring, MD (US);
Gerald Walter Fischer, Bethesda, MD (US);
Biosynexus Incorporated, Gaithersburg, MD (US);
Abstract
The present invention encompasses monoclonal antibodies that bind to lipoteichoic acid (LTA) of Gram positive bacteria. The antibodies also bind to whole bacteria and enhance phagocytosis and killing of the bacteria in vitro. The invention also provides antibodies having human sequences (chimeric, humanized and human antibodies). The invention also sets forth the variable regions of three antibodies within the invention and presents the striking homology between them.