Company Filing History:
Years Active: 2017-2023
Title: Alan Hunter: Innovator in Protein Purification
Introduction
Alan Hunter is a notable inventor based in Gaithersburg, MD (US). He has made significant contributions to the field of protein purification, holding a total of 8 patents. His work focuses on enhancing the stability and bioactivity of proteins, which is crucial for various applications in biotechnology and pharmaceuticals.
Latest Patents
One of his latest patents is titled "Method of purifying albumin-fusion proteins." This invention relates to a method that reduces the level of oxidation of susceptible amino acid residues in albumin-fusion proteins. The method involves an affinity matrix chromatography step followed by an anion exchange chromatography step. The resulting purified albumin-fusion proteins exhibit low levels of oxidation and maintain their enhanced half-life in vivo, along with their bioactivity. In some embodiments, the albumin-fusion protein includes a scaffold, such as the human Tenascin C scaffold. Additionally, he has developed a "Method for purifying active polypeptides or immunoconjugates." This invention provides methods for isolating an active polypeptide or immunoconjugate by purifying a solution that contains both the active component and an acidic variant, such as a deamidated variant, using anion exchange chromatography. The invention also includes compositions, formulations, and unit dosage forms comprising the purified polypeptide or immunoconjugate.
Career Highlights
Throughout his career, Alan Hunter has worked with prominent companies in the biotechnology sector, including MedImmune Limited. His expertise in protein purification has made him a valuable asset in the development of innovative biopharmaceutical products.
Collaborations
Alan has collaborated with notable professionals in his field, including Christopher D. Thompson and Thomas Linke. These collaborations have further enhanced his research and development efforts in protein purification technologies.
Conclusion
Alan Hunter is a distinguished inventor whose work in protein purification has led to significant advancements in biotechnology. His innovative methods and collaborations continue to impact the field positively.