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Exton, PA, United States of America

3-Dimensional Pharmaceuticals, Inc.

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USPTO Granted Patents = 77

% Expired Patents = 5.2

Forward Citations = 1,551

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93 inventors (with patents filed for the assignee):

Bruce Edward Tomczuk (32 out of 44 patents)

Richard M Soll (32 out of 71 patents)

Tianbao Lu (30 out of 65 patents)

4. Thomas P Markotan (19 out of 30 patents)

5. Francis Raymond Salemme (18 out of 30 patents)

6. Carl R Illig (17 out of 90 patents)

7. Roger Francis Bone (16 out of 24 patents)

8. Michael W Pantoliano (14 out of 24 patents)

9. Nalin L Subasinghe (12 out of 12 patents)

10. Barry A Springer (9 out of 13 patents)

11. Dimitris K Agrafiotis (9 out of 20 patents)

12. Colleen Siedem (8 out of 10 patents)

13. Cynthia L Fedde (7 out of 8 patents)

14. M Jonathan Rudolph (6 out of 12 patents)

15. Alexander W Rhind (6 out of 7 patents)

Core Competencies:

Protease Inhibitors

Integrin Antagonists

Complement Cascade Inhibitors

Aminoguanidines

Thromboresistant Materials

Human Basic Fibroblast Growth Factor

Quinazolinones

Azacycloalkanones

Thiophene Amidines

Heteroaryl Compounds

Chemical Compound Generation

Microplate Thermal Shift Assay

77 patents: Sort by Forward Citations

1. 7482376 - Conjugated complement cascade inhibitors (2009-01-27),

2. 7429603 - C-fms kinase inhibitors (2008-09-30),

3. 7241789 - Substituted indoles and their use as integrin antagonists (2007-07-10),

4. 7138530 - Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions (2006-11-21),

5. 7138374 - Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, asparate 101 or leucine 137 (2006-11-21),

6. 7109354 - Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions (2006-09-19),

7. 7060706 - Quinazolinones (2006-06-13),

8. 6962942 - Azacycloalkanone serine protease inhibitors (2005-11-08),

9. 6900231 - Aminopyridyl-substituted phenyl acetamides as protease inhibitors (2005-05-31),

10. 6890930 - Quinazolinones (2005-05-10),

11. 6872730 - Substituted benzofurans and benzothiophenes, methods of making and methods of use as integrin antagonists (2005-03-29),

12. 6767722 - Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, Aspartate 101 or Leucine 137 (2004-07-27),

13. 6737404 - Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, aspartate 101 or leucine 137 (2004-05-18),

14. 6730783 - Process for preparing aminoguanidines and alkoxyguanidines as protease inhibitors (2004-05-04),

15. 6706765 - Aminoguanidines and alkoxyguanidines as protease inhibitors (2004-03-16),

Company Overview

3-Dimensional Pharmaceuticals, Inc., based in Exton, Pennsylvania, specializes in the development of innovative therapeutic solutions, primarily focusing on protease inhibitors. The company is engaged in advanced research across several core technology areas, including integrin antagonists and complement cascade inhibitors. Their expertise extends to the creation of thromboresistant materials and various chemical compounds, such as aminoguanidines and quinazolinones, aimed at addressing complex medical challenges.

Profile summary synthesized from public USPTO records and patent filings.

Company Badge

USPTO Data Jan 1 1976 - Nov 3 2026

77 Patents

#4 in Exton, PA

#180 in Pennsylvania

#4,796 in US

#9,785 in the World

Exton, PA, United States of America

3-Dimensional Pharmaceuticals, Inc.

Forward Citations = 1,551

93 inventors:

Bruce Edward Tomczuk (32 out of 44 patents)

Richard M Soll (32 out of 71 patents)

Tianbao Lu (30 out of 65 patents)

4. Thomas P Markotan (19 out of 30 patents)

5. Francis Raymond Salemme (18 out of 30 patents)

IDiyas Innovation Intelligence. (2026). Company Patent Portfolio: 3-Dimensional Pharmaceuticals, Inc.. Retrieved from https://idiyas.com/company/3-dimensional-pharmaceuticals

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]

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