The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 2004
Filed:
Apr. 05, 2001
Applicant:
Inventors:
Barry A. Springer, Wilmington, DE (US);
Michael W. Pantoliano, Boxford, PA (US);
Celia M. Sharp, Doylestown, PA (US);
Assignee:
3-Dimensional Pharmaceuticals, Inc., Exton, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/818 ; C07K 1/450 ;
U.S. Cl.
CPC ...
A61K 3/818 ; C07K 1/450 ;
Abstract
The present invention relates to novel muteins of human basic fibroblast growth factor with superagonist properties. Both protein and the respective encoding nucleic acid species are disclosed. The invention also embodies vectors and host cells for the propagation of said nucleic acid sequences and the production of said muteins. Also disclosed are methods for stimulating cell division, treating a wound, treating ischemia, treating heart disease, treating neural injury, treating peripheral vascular disease, treating a gastric ulcer and treating a duodenal ulcer.