The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2012

Filed:

Mar. 18, 2011
Applicants:

Xiaodong LI, San Diego, CA (US);

Andrew Patron, San Marcos, CA (US);

Catherine Tachdjian, San Diego, CA (US);

Hong Xu, San Diego, CA (US);

Qing LI, San Diego, CA (US);

Alexey Pronin, San Diego, CA (US);

Guy Servant, San Diego, CA (US);

Lan Zhang, San Diego, CA (US);

Thomas Brady, San Diego, CA (US);

Vincent Darmohusodo, San Diego, CA (US);

Melissa Arellano, San Diego, CA (US);

Victor Selchau, San Diego, CA (US);

Brett Weylan Ching, San Diego, CA (US);

Donald S. Karanewsky, Escondido, CA (US);

Paul Brust, San Diego, CA (US);

Jing Ling, Carlsbad, CA (US);

Wen Zhao, San Diego, CA (US);

Chad Priest, Encinitas, CA (US);

Inventors:

Xiaodong Li, San Diego, CA (US);

Andrew Patron, San Marcos, CA (US);

Catherine Tachdjian, San Diego, CA (US);

Hong Xu, San Diego, CA (US);

Qing Li, San Diego, CA (US);

Alexey Pronin, San Diego, CA (US);

Guy Servant, San Diego, CA (US);

Lan Zhang, San Diego, CA (US);

Thomas Brady, San Diego, CA (US);

Vincent Darmohusodo, San Diego, CA (US);

Melissa Arellano, San Diego, CA (US);

Victor Selchau, San Diego, CA (US);

Brett Weylan Ching, San Diego, CA (US);

Donald S. Karanewsky, Escondido, CA (US);

Paul Brust, San Diego, CA (US);

Jing Ling, Carlsbad, CA (US);

Wen Zhao, San Diego, CA (US);

Chad Priest, Encinitas, CA (US);

Assignee:

Senomyx, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 261/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals.


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