Location History:
- Wuxi, CN (2020)
- Jiangsu, CN (2022)
Company Filing History:
3 out of 526 
1 out of 1 Years Active: 2020-2022
Title: Zhijie Hu: Innovator in Continuous Culture and Citrate Production
Introduction
Zhijie Hu is a notable inventor based in Wuxi, China. He has made significant contributions to the field of biotechnology, particularly in the area of continuous culture methods and citrate production. With a total of 3 patents, his work addresses critical challenges in fermentation processes.
Latest Patents
Zhijie Hu's latest patents include innovative methods for enhancing the production of citric acid. One of his patents, titled "Aspergillus niger seed continuous culture and method for producing citric acid therefrom," outlines a comprehensive approach to continuous culture. This method involves inoculating spores into a seed culture medium, performing continuous dispersion treatment, and ultimately transferring the seed liquid into a fermentation medium for culture. This breakthrough effectively addresses the slow growth of multi-cellular filamentous bacteria and the loss of mycelium pellets during continuous culture.
Another significant patent is the "Method for reconstructing Aspergillus niger to increase citrate production." This invention focuses on genome reconstruction by inserting a low affinity glucose transporter gene, LGT1, into the genome. The resulting strain demonstrates improved tolerance to higher fermentation temperatures and lower pH levels, leading to enhanced production, yield, and purity of citric acid compared to the parental strain.
Career Highlights
Zhijie Hu has worked with esteemed institutions such as Jiangnan University and Jiangsu Guoxin Union Energy Co., Ltd. His experience in these organizations has contributed to his expertise in biotechnology and fermentation processes.
Collaborations
Zhijie Hu has collaborated with notable colleagues, including Xiaodong Jiang and Sai Jin. Their combined efforts have further advanced research in the field of biotechnology.
Conclusion
Zhijie Hu's innovative work in continuous culture and citrate production showcases his significant contributions to biotechnology. His patents reflect a commitment to solving complex challenges in fermentation processes, making him a valuable figure in the field.
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