The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2020
Filed:
Jan. 11, 2018
Jiangnan University, Wuxi, CN;
Jiangsu Guoxin Union Energy CO Ltd, Wuxi, CN;
Long Liu, Wuxi, CN;
Jian Chen, Wuxi, CN;
Guocheng Du, Wuxi, CN;
Jianghua Li, Wuxi, CN;
Xian Yin, Wuxi, CN;
Zhijie Hu, Wuxi, CN;
Jianwei Jiang, Wuxi, CN;
Fuxin Sun, Wuxi, CN;
Sai Jin, Wuxi, CN;
Cheng Zhang, Wuxi, CN;
Xiaodong Jiang, Wuxi, CN;
JIANGNAN UNIVERSITY, Wuxi, CN;
Abstract
The invention discloses a method for improving citric acid production byfermentation, which integratesGABA pathway succinate semialdehyde dehydrogenase SSD gene intogenome to obtain recombinantstrain, and uses recombinant black Thestrain ferments to produce citric acid; the expression of the succinate semialdehyde dehydrogenase SSD gene is regulated by the Pgas promoter. The method of the invention realizes the expression of succinate semialdehyde dehydrogenase SSD into enhance the GABA pathway so as to strengthen the TCA cycle and promote the synthesis of citric acid.