Richmond, CA, United States of America

Yuqiao Shen


Average Co-Inventor Count = 3.7

ph-index = 2

Forward Citations = 7(Granted Patents)


Location History:

  • Orinda, CA (US) (2008)
  • Richmond, CA (US) (2003 - 2010)

Company Filing History:


Years Active: 2003-2010

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6 patents (USPTO):Explore Patents

Title: Innovations of Yuqiao Shen in Cancer Treatment

Introduction

Yuqiao Shen is a notable inventor based in Richmond, CA, who has made significant contributions to the field of cancer treatment through his innovative research and patents. With a total of six patents to his name, Shen's work focuses on enhancing the efficacy of adenoviral mutants for therapeutic applications.

Latest Patents

One of Yuqiao Shen's latest patents is titled "Adenovirus E1B-55K single amino acid mutants and methods of use." This patent describes adenoviral mutants that possess single amino acid mutations in the E1B-55K protein. These mutations affect the p53 binding and inactivation, as well as the late functions of the E1B-55K protein, thereby improving the effectiveness of these viruses in treating cancer compared to adenoviral mutants with the E1B-55K region deleted. Another significant patent involves a new cytosine deaminase gene and protein, which demonstrates an increased ability to convert the 5-fluorocytosine prodrug into its toxic form, showcasing its potential in cancer therapy.

Career Highlights

Yuqiao Shen is currently associated with Onyx Pharmaceuticals, Inc., where he continues to advance his research in the field of oncology. His work has garnered attention for its innovative approach to utilizing adenoviral vectors in cancer treatment.

Collaborations

Shen collaborates with esteemed colleagues, including Sylvie Laquerre and Terry Hermiston, who contribute to the research and development efforts at Onyx Pharmaceuticals.

Conclusion

Yuqiao Shen's innovative work in the field of cancer treatment through his patents highlights the potential of adenoviral mutants and novel proteins in enhancing therapeutic efficacy. His contributions are paving the way for advancements in cancer therapies.

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