The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2009

Filed:

Jul. 20, 2006
Applicants:

Yuqiao Shen, Richmond, CA (US);

Sylvie Laquerre, Exton, PA (US);

Amy M. Delaney, Belleville, MI (US);

Charles A. Omer, Ann Arbor, MI (US);

Inventors:

Yuqiao Shen, Richmond, CA (US);

Sylvie Laquerre, Exton, PA (US);

Amy M. Delaney, Belleville, MI (US);

Charles A. Omer, Ann Arbor, MI (US);

Assignee:

Onyx Pharmaceuticals, Inc., Emeryville, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12P 21/00 (2006.01); C07H 21/00 (2006.01); C12N 9/78 (2006.01); C12Q 1/34 (2006.01); C12N 5/10 (2006.01); C12N 1/21 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A new cytosine deaminase gene and protein fromare provided. This protein has increased ability to convert the 5-fluorocytosine prodrug to its toxic form when compared against theenzyme.


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