The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2008
Filed:
Nov. 25, 2002
Applicants:
Leisa Johnson, Lafayette, CA (US);
Ali Fattaey, San Francisco, CA (US);
Terry Hermiston, Corte Madera, CA (US);
Yuqiao Shen, Orinda, CA (US);
Sylvie Laquerre, Conshohocken, PA (US);
Inventors:
Leisa Johnson, Lafayette, CA (US);
Ali Fattaey, San Francisco, CA (US);
Terry Hermiston, Corte Madera, CA (US);
Yuqiao Shen, Orinda, CA (US);
Sylvie Laquerre, Conshohocken, PA (US);
Assignee:
Onyx Pharmaceuticals, Inc., Emeryville, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Viral vectors and methods of making such vectors are described that preferentially kill neoplastic but not normal cells, the preferred vector being an adenovirus that has the endogenous promoters in the E1A and/or E4 regions substituted with a tumor specific promoter which is preferably E2F responsive.