This inventor holds 4 USPTO granted patents and 1 EPO patent. Top assignee: Onyx Pharmaceuticals, Inc.. Active years: 2006-2010.
Location History:
- Lafayette, CA (US) (2006 - 2008)
- Richmond, CA (US) (2006 - 2010)
Company Filing History:
Years Active: 2006-2010
Title: Leisa Johnson: Innovator in Adenoviral Vector Technology
Introduction
Leisa Johnson is a prominent inventor based in Richmond, CA (US). She has made significant contributions to the field of biotechnology, particularly in the development of adenoviral vectors for treating diseases. With a total of 4 patents to her name, her work focuses on innovative solutions for complex medical challenges.
Latest Patents
One of her latest patents involves adenoviral vectors designed for treating diseases. These vectors include mutant adenoviruses that possess restriction sites in the E3 region, allowing for partial or total deletion of specific genes. This technology facilitates the substitution of heterologous genes in the E3 region, which are operably linked to endogenous adenoviral transcriptional control sequences. The resulting expression pattern mimics that of the endogenous adenoviral genes, providing potential applications for diagnosing or treating diseases, particularly those involving unwanted cell growth, such as cancer. Another notable patent is related to oncolytic adenoviruses, which are viral vectors engineered to preferentially kill neoplastic cells while sparing normal cells. This is achieved by substituting endogenous promoters in the E1A and/or E4 regions with tumor-specific promoters, enhancing the therapeutic potential of these vectors.
Career Highlights
Leisa Johnson is currently associated with Onyx Pharmaceuticals, Inc., where she continues to advance her research in adenoviral vector technology. Her innovative work has positioned her as a key figure in the biotechnology sector, contributing to the development of therapies that could significantly impact cancer treatment.
Collaborations
Throughout her career, Leisa has collaborated with notable professionals in her field, including Terry Hermiston and Ali Fattaey. These collaborations have further enriched her research and expanded the scope of her innovative projects.
Conclusion
Leisa Johnson's contributions to the field of biotechnology, particularly in adenoviral vector technology, highlight her role as a leading inventor. Her work not only advances scientific understanding but also holds promise for future medical applications.