Location History:
- Moshav Beit Hillel, IL (2010)
- Doar-Na Galil Elyon, IL (2011)
- Moshav Beit-Hillel Doar-Na Galil Elyon, IL (2012)
- Kibbutz HaSolelim-Doar-Na HaMovil, IL (2012 - 2014)
- Kibbutz HaSolelim, IL (2014 - 2017)
- Doar-Na HaMovil, IL (2019)
- Timrat, IL (2015 - 2023)
Company Filing History:
23 out of 25 
1 out of 60 
1 out of 169 Years Active: 2010-2025
Title: **Yoseph Shaaltiel: Innovator in Therapeutic Protein Treatments**
Introduction
Yoseph Shaaltiel, based in Timrat, IL, is a prolific inventor with an impressive portfolio boasting 22 patents. His innovation primarily focuses on therapeutic proteins, particularly in the treatment of rare genetic disorders like Fabry disease. His contributions have significantly advanced the field of biotechnology, specifically in enhancing patient care through improved therapeutic methods.
Latest Patents
Among his latest inventions is a therapeutic regimen for treating Fabry disease through stabilized alpha-galactosidase. This groundbreaking method involves administering a stabilized plant recombinant human alpha-galactosidase protein, which is covalently linked in pairs, boasting exceptional safety protocols and intervals of over two weeks between administrations. Clinical outcomes reveal notable improvements in patients, particularly regarding reduced Gb3 accumulation, pain management, gastrointestinal parameters, and kidney and cardiac stabilization.
Another significant patent involves a modified DNase I protein where specific amino acids have been modified non-cellularly. This innovation enhances DNA hydrolytic activity, especially in the presence of actin, compared to its non-modified counterparts. The potential applications of this modified DNase I protein include reducing DNA content in sputum and treating conditions associated with excess extracellular DNA.
Career Highlights
Yoseph Shaaltiel has made meaningful contributions while working at prominent companies such as Protalix Ltd. and Compugen Ltd. Corporation. His work at these organizations underscores his commitment to advancing therapeutic innovations and developing solutions that address complex medical conditions.
Collaborations
Throughout his career, Shaaltiel has collaborated with notable professionals, including Tali Kizhner and Avidor Shulman. These partnerships have fostered an environment of innovation, driving forward the development of new therapeutic approaches in biotechnology.
Conclusion
Yoseph Shaaltiel's remarkable journey as an inventor highlights the crucial role of innovation in advancing healthcare solutions. His inventions, particularly in therapeutic regimens and modified proteins, not only reflect his expertise but also his dedication to improving patient outcomes. As he continues to innovate, his work stands to make a profound impact on the future of medical treatment.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.