The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 19, 2018
Filed:
Sep. 10, 2015
Applicant:
Protalix Ltd., Carmiel, IL;
Inventors:
Yoseph Shaaltiel, Timrat, IL;
Uri Hanania, Carmiel, IL;
Tali Kizhner, Yishuv Atzmon-Segev, IL;
Tami Ariel, Misgav, IL;
Svetlana Gingis-Velitski, Kiryat-Motzkin, IL;
Myriam Golembo, Moshav Netaim, IL;
Assignee:
Protalix Ltd., Carmiel, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/705 (2006.01); A61K 38/17 (2006.01); A61K 36/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70578 (2013.01); A61K 38/1793 (2013.01); A61K 36/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/30 (2013.01);
Abstract
A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.