Yanyan Han

Title: **Yanyan Han: A Pioneer in Cancer Immunotherapy**

Introduction

Yanyan Han, an innovative inventor located in Shenzhen, China, has made significant contributions to the field of cancer immunotherapy. With a total of nine patents to his name, he has advanced methods for enhancing immune responses against tumors, significantly impacting treatment strategies.

Latest Patents

Among his latest innovations, Yanyan Han has developed groundbreaking patents including:

1. **Methods of Obtaining Tumor-Specific T Cell Receptors**: This patent provides methods for obtaining a variety of T cell receptors that specifically recognize target tumor antigen peptides from patients who have benefited from immunotherapy, such as multiple antigen-specific cell therapy. It also encompasses engineered immune cells expressing these TCRs and methods for treating diseases using the modified immune cells.

2. **Methods of Cancer Treatment Using Activated T Cells**: This invention outlines a comprehensive method for treating cancer using activated T cells or peripheral blood mononuclear cells (PBMCs) induced by antigen-presenting cells, such as dendritic cells loaded with diverse tumor antigen peptides. The approach can be administered alone or alongside immune checkpoint inhibitors, with additional methods for preparing activated T cells and monitoring treatment outcomes.

3. **Precision Therapy Methods Customized for Individuals**: This patent focuses on personalized treatment methods using neoantigen peptides tailored to an individual’s tumor mutation load. It includes processes for cloning tumor-specific T cell receptors and provides compositions and kits beneficial for cancer immunotherapy.

Career Highlights

Yanyan Han has been associated with leading companies in the biotech sector, such as Syz Cell Therapy Co. and Hryz (Shenzhen) Biotech Co. His work within these organizations has propelled advancements in T cell therapies and has solidified his reputation as a thought leader in immunotherapeutic innovations.

Collaborations

Throughout his career, Han has collaborated with notable professionals, including Xiangjun Zhou and Dongyun Wu. These partnerships have further enhanced his research and the development of novel cancer therapies that show great promise in clinical settings.

Conclusion

Yanyan Han stands out as a key inventor in the realm of cancer immunotherapy, leveraging his expertise to develop pioneering methods that hold the potential to transform treatment paradigms. With a robust portfolio of patents and meaningful collaborations, his contributions are paving the way for future innovations in the fight against cancer.