The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 2022
Filed:
Mar. 29, 2019
Applicants:
Syz Cell Therapy Co., Guangdong, CN;
Hryz (Shenzhen) Biotech Co., Guangdong, CN;
Inventors:
Xiangjun Zhou, Shenzhen, CN;
Yifan Ma, Shenzhen, CN;
Yanyan Han, Guangdong, CN;
Jin Li, Shenzhen, CN;
Longqing Tang, Shenzhen, CN;
Junyun Liu, Shenzhen, CN;
Dongyun Wu, Shenzhen, CN;
Assignees:
SYZ Cell Therapy Co., Guangdong, CN;
HRYZ (Shenzhen) Biotech Co., Guangdong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 35/17 (2015.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0638 (2013.01); A61K 35/17 (2013.01); A61P 35/00 (2018.01); C12N 2501/02 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/2321 (2013.01); C12N 2501/24 (2013.01); C12N 2501/50 (2013.01); C12N 2501/515 (2013.01); C12N 2501/999 (2013.01); C12N 2502/1121 (2013.01);
Abstract
The present invention provides methods of preparing a population of activated T cells by co-culturing T cells with dendritic cells loaded with a plurality of tumor antigen peptides. Also provided are methods of treating cancer in an individual using the activated T cells, pharmaceutical compositions and kits for cell-based cancer immunotherapy.