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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11390659 B1

PDFFull Text
Date of Patent:
Jul. 19, 2022

Filed:

Apr. 12, 2019

Methods of obtaining tumor-specific t cell receptors

Applicants:

Syz Cell Therapy Co., Guangdong, CN;

Hryz (Shenzhen) Biotech Co., Guangdong, CN;

Inventors:

Xiangjun Zhou, Shenzhen, CN;

Yanyan Han, Shenzhen, CN;

Xiaoling Liang, Shenzhen, CN;

Xihe Chen, Shenzhen, CN;

Assignees:

SYZ Cell Therapy Co., Guangdong, CN;

HRYZ (Shenzhen) Biotech Co., Guangdong, CN;

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Maria Marvich

Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 35/00 (2006.01); C12N 5/078 (2010.01); C12N 5/22 (2006.01); C07K 14/725 (2006.01); A61K 39/00 (2006.01); C12N 5/0783 (2010.01); C12N 5/0784 (2010.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 39/0011 (2013.01); A61P 35/00 (2018.01); C12N 5/0636 (2013.01); C12N 5/0639 (2013.01); C12P 21/02 (2013.01); A61K 38/00 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5158 (2013.01); C12N 2502/1114 (2013.01); C12N 2502/1121 (2013.01);
Abstract

Provided methods of obtaining a plurality of T cell receptors specifically recognizing a target tumor antigen peptide from an individual that has clinically benefitted from an immunotherapy, such as Multiple Antigen Specific Cell Therapy. Also provided tumor-specific TCRs, engineered immune cells expressing the TCRs and methods of treating a disease using the engineered immune cells.

Find Patent Forward Citations

Zhou, Xiangjun. (2022). Methods of obtaining tumor-specific t cell receptors (U.S. Patent No. 11390659). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11390659

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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