Wolf B Frommer

Title: The Innovative Mind of Wolf B Frommer

Introduction

Wolf B Frommer is a renowned inventor based in Washington, DC, whose remarkable contributions to the field of biochemistry have led to the issuance of 12 patents. His work predominantly focuses on the complex mechanisms of cellular metabolism and sugar transport, providing invaluable insights that have implications in both human health and agriculture.

Latest Patents

Among his latest innovations is a genetically encoded probe designed for the quantification of lactate and methods for measuring metabolic rates and lactate transport. This advanced nanosensor enables the detection and quantification of lactate in various types of samples, including tissues and intracellular compartments, with exceptional spatial and temporal resolution. The patented methods utilize the nanosensor to assess the activity of lactate transporters, monitor cellular lactate production and consumption, and evaluate the rate of mitochondrial pyruvate consumption. Furthermore, these methodologies have the potential to quantify the transformation in energy metabolism characteristic of cancer cells at a single-cell resolution, as well as to detect how candidate drugs interfere with mitochondrial energetics.

Additionally, Frommer has developed a novel class of transporter proteins, known as SWEET, GLUE, or Glu. These transporters facilitate the transportation of sugars across cellular membranes, offering a new system to manipulate sugar concentrations within various organs and organelles. This technology not only deepens the understanding of sugar transport mechanisms but also aims to enhance plant resilience against pathogenic attacks.

Career Highlights

Wolf B Frommer’s career includes significant tenures at prestigious institutions, including the Carnegie Institution of Washington and Leland Stanford Junior University. His expertise has positioned him at the forefront of research in biochemistry and molecular biology, driving innovations that bridge fundamental research and practical applications.

Collaborations

Throughout his career, Frommer has collaborated with esteemed colleagues such as Loren Looger and Sylvie Lalonde. These collaborations have enhanced his research endeavors, contributing to the development of groundbreaking technologies and novel insights in the field of metabolic research.

Conclusion

In summary, Wolf B Frommer is an influential inventor whose pioneering work has led to significant advancements in the understanding of metabolic processes and sugar transport. His innovative patents not only advance scientific knowledge but also promise practical applications that may transform medical and agricultural fields. With a commitment to innovation and collaboration, Frommer continues to push the boundaries of science, making a lasting impact on both current and future research.