The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2010
Filed:
Oct. 14, 2005
Applicants:
Sakiko Okumoto, Washington, DC (US);
Loren L. Looger, Washington, DC (US);
Wolf B. Frommer, Washington, DC (US);
Inventors:
Sakiko Okumoto, Washington, DC (US);
Loren L. Looger, Washington, DC (US);
Wolf B. Frommer, Washington, DC (US);
Assignee:
Carnegie Institution of Washington, Washington, DC (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); C12N 1/00 (2006.01); C12N 1/20 (2006.01); G01N 33/53 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Neurotransmitter biosensors are disclosed, including YbeJ-based glutamate binding biosensors, comprising a neurotransmitter binding domain conjugated to donor and fluorescent moieties that permit detection and measurement of Fluorescence Resonance Energy Transfer upon binding neurotransmitter. Such biosensors are useful for the detection of neurotransmitter concentrations in vivo and in culture.