Company Filing History:
Years Active: 2010-2013
Title: Loren Looger: Innovator in Biosensor Technology
Introduction
Loren Looger is a prominent inventor based in Washington, DC, known for his significant contributions to the field of biosensor technology. With a total of 4 patents, he has made remarkable advancements that enhance the sensitivity and stability of biosensors used in various applications.
Latest Patents
Loren's latest patents include the development of sensitive FRET sensors and methods of using the same. These intramolecular biosensors utilize a ligand binding domain fused to donor and fluorescent moieties, allowing for the detection and measurement of Fluorescence Resonance Energy Transfer upon ligand binding. Notably, at least one of the donor and fluorescent moieties may be internally fused to the biosensor, ensuring that both ends of the internally fused fluorophore are fixed. Additionally, he has provided methods to improve the sensitivity of terminally fused biosensors, which are valuable for detecting and quantifying ligands in vivo and in culture. Another significant patent focuses on environmentally stable biosensors, which incorporate a ligand binding domain from a thermophilic organism. These biosensors demonstrate enhanced acid, thermal, and chemical stability compared to those constructed using protein domains from mesophilic organisms.
Career Highlights
Loren Looger is affiliated with the Carnegie Institution of Washington, where he continues to push the boundaries of biosensor technology. His work has been instrumental in developing innovative solutions that address critical challenges in the detection and quantification of biological ligands.
Collaborations
Throughout his career, Loren has collaborated with notable scientists, including Wolf B. Frommer and Sakiko Okumoto. These partnerships have further enriched his research and contributed to the advancement of biosensor technology.
Conclusion
Loren Looger's innovative work in biosensor technology has established him as a leading inventor in the field. His patents reflect a commitment to enhancing the sensitivity and stability of biosensors, paving the way for future advancements in biological detection methods.