William Aloysius Nugent

This inventor holds 11 USPTO granted patents and 3 published patent applications, plus 2 CIPO patents and 5 EPO patents. Top assignees: Vertex Pharmaceuticals, Inc., Alios Biopharma, Inc.. Active years: 2013-2025.

IDiyas Innovation Intelligence. (2026). Inventor Profile: William Aloysius Nugent. Retrieved from https://idiyas.com/inventor/william-aloysius-nugent

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 11 (Patent Applications = 3)

% Patents Active = 54.5

CIPO Patents = 2 (Patent Applications = 3)

EPO Patents = 5 (Patent Applications = 8)

Average Co-Inventor Count = 6.3

ph-index = 5

Forward Citations = 66(Granted Patents)

Location History:

Cambridge, MA (US) (2013)
Manomet, MA (US) (2014 - 2022)
Noblesville, IN (US) (2018 - 2022)

Company Filing History:

9 out of 1,168

Vertex Pharmaceuticals, Inc.

patents

2 out of 44

Alios Biopharma, Inc.

patents

Years Active: 2013-2025

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11 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12415798 - Processes for making modulators of cystic fibrosis transmembrane conductance regulator (2025-09-16),

2. 11465985 - Processes for making modulators of cystic fibrosis transmembrane conductance regulator (2022-10-11),

3. 11434201 - Processes for preparing pyrrolidine compounds (2022-09-06),

4. 11345700 - Methods of preparing inhibitors of influenza viruses replication (2022-05-31),

5. 10640501 - Methods of preparing inhibitors of influenza viruses replication (2020-05-05),

6. 10071979 - Process of producing cycloalkylcarboxamido-indole compounds (2018-09-11),

7. 10023569 - Methods of preparing inhibitors of influenza viruses replication (2018-07-17),

8. 9856284 - Solid forms of a thiophosphoramidate nucleotide prodrug (2018-01-02),

9. 9394330 - Solid forms of a thiophosphoramidate nucleotide prodrug (2016-07-19),

10. 8916538 - Solid forms of a thiophosphoramidate nucleotide prodrug (2014-12-23),

11. 8378124 - Preparation of protected alpha-keto beta-amino esters and amides (2013-02-19),

Title: The Innovations of William Aloysius Nugent

Introduction

William Aloysius Nugent, an accomplished inventor based in Manomet, MA, holds a remarkable portfolio of ten patents. His innovative contributions focus primarily on pharmaceutical compounds that target medical conditions, showcasing his commitment to advancing healthcare solutions.

Latest Patents

Nugent's recent work includes innovative processes for making modulators of the cystic fibrosis transmembrane conductance regulator. This patent outlines detailed methods for preparing compounds that hold the potential for significant therapeutic applications. Additionally, he has developed processes for preparing a variety of pyrrolidine compounds, including 5,5-dimethyl-3-methylenepyrrolidin-2-one and both (S)- and (R)-3,5,5-trimethylpyrrolidine-2-one, alongside their respective salt forms. These advances not only bolster his reputation as an inventor but also contribute substantially to the pharmaceutical field.

Career Highlights

Throughout his career, Nugent has made substantial strides in the biotechnology sector. He has worked with notable companies such as Vertex Pharmaceuticals, Inc. and Alios Biopharma, Inc. His time at these organizations allowed him to further refine his skills and expertise in drug development, resulting in numerous impactful innovations.

Collaborations

In addition to his work, Nugent has collaborated with esteemed colleagues like Gerald J. Tanoury and Peter Jamison Rose. These partnerships highlight his ability to work within a team of skilled professionals, fostering collaborative innovation in research and development.

Conclusion

William Aloysius Nugent stands out as a prominent figure in the realm of inventions, particularly in pharmaceutical innovations. Through his smart approach to problem-solving and dedication to improving health outcomes, he continues to make significant contributions that have the potential to impact countless lives. His work exemplifies the spirit of innovation that drives progress in science and medicine today.

Profile summary based on public USPTO records.