The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2014
Filed:
Mar. 11, 2013
Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);
Anuj K. Kuldipkumar, Medford, MA (US);
Ales Medek, Winchester, MA (US);
Lori Ann Ferris, Medford, MA (US);
Praveen Mudunuri, Waltham, MA (US);
Young Chun Jung, Lexington, MA (US);
David Richard Willcox, Wellesley, MA (US);
Michael Waldo, Grafton, MA (US);
William Aloysius Nugent, Manomet, MA (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
The present application relates to solid state forms, for example, crystalline forms of 2'-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, pharmaceutical compositions that can include one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate, and methods of treating or ameliorating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate. Also disclosed herein are methods of treating diseases and/or conditions with one or more solid forms of 2′-C-methyluridine-5′-(O-phenyl-N—(S)-1-(isopropoxycarbonyl)ethyl)thiophosphoramidate in combination with one or more other agents.