The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2018
Filed:
Apr. 15, 2015
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Gerald J. Tanoury, Marlborough, MA (US);
Cristian Harrison, Beverly, MA (US);
Benjamin Joseph Littler, Carlsbad, CA (US);
Peter Jamison Rose, Littleton, MA (US);
Robert Michael Hughes, San Diego, CA (US);
Young Chun Jung, Lexington, MA (US);
David Andrew Siesel, San Diego, CA (US);
Elaine Chungmin Lee, Arlington, MA (US);
Daniel T. Belmont, Grafton, MA (US);
William A. Nugent, Noblesville, IN (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
The present invention features processes for preparing compounds, such as (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1), useful for treating CFTR mediated diseases such as cystic fibrosis.