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Years Active: 2019-2025
Title: **Wesley Sundquist: Innovating in Polypeptide Assemblies**
Introduction
Wesley Sundquist is a notable inventor based in Salt Lake City, Utah. He has contributed significantly to the field of protein science and biotechnology through his innovative inventions, holding a total of three patents. His work focuses on developing advanced polypeptide assemblies, which have substantial potential in medical and research applications.
Latest Patents
Sundquist's latest patent details the design and methodology of polypeptide assemblies. This innovation involves multimeric assemblies comprising multiple oligomeric substructures, where each substructure includes proteins that self-interact around a rotational symmetry axis. Notably, each protein is engineered with a polypeptide-polypeptide interface ('O interface') and domains that facilitate membrane scission. This mechanism allows for the release of enveloped multimeric assemblies from cells by engaging the ESCRT machinery at the site of budding. The assembly also integrates polypeptide domains capable of interacting with lipid bilayers, providing valuable insights into cellular processes and potential therapeutic applications.
Career Highlights
Wesley Sundquist has had a distinguished career, contributing to significant research and development initiatives. He has been associated with prominent institutions such as the University of Utah Research Foundation and the University of Washington, enriching his academic and practical experience in the field.
Collaborations
Throughout his career, Sundquist has collaborated with notable figures in the research community, including Neil P. King and Joerg Votteler. These partnerships highlight his commitment to advancing scientific understanding and technology through teamwork and innovation.
Conclusion
Wesley Sundquist stands out as a pioneering inventor whose work on polypeptide assemblies has the potential to transform various scientific and medical fields. His patents are a testament to his ongoing contributions and influence in the biotechnology sector, marking him as a significant figure in contemporary research and innovation.