The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Oct. 25, 2019
Applicant:

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Jörg Philip Votteler, Murray, UT (US);

Wesley I. Sundquist, Salt Lake City, UT (US);

Neil P. King, Seattle, WA (US);

Assignee:

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); A61K 47/69 (2017.01); C07K 14/01 (2006.01); C07K 14/075 (2006.01); C07K 14/08 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/08 (2013.01); A61K 47/6901 (2017.08); C07K 14/075 (2013.01); C12N 7/00 (2013.01); C12N 2710/10042 (2013.01); C12N 2770/30032 (2013.01); C12N 2770/30042 (2013.01);
Abstract

Disclosed herein are modified capsid proteins comprising a capsid forming protein, a membrane binding element and an ESCRT-recruiting element, wherein at least one of the membrane binding element and the ESCRT-recruiting element is heterologous to the capsid forming protein. Disclosed are capsids comprising a plurality of modified capsid proteins. Disclosed are multimeric assemblies comprising a plurality of capsids within a membrane. Also disclosed are modified non-enveloped viruses comprising a capsid wherein the capsid comprises a plurality of modified capsid proteins, wherein the plurality of modified capsid proteins comprise a capsid forming protein, a membrane binding element and an ESCRT-recruiting element, wherein at least one of the membrane binding element and the ESCRT-recruiting element is heterologous to the modified capsid protein, wherein the capsid forming protein is a capsid forming protein of a non-enveloped virus.


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