Company Filing History:
13 out of 88 
1 out of 3 Years Active: 1997-2011
Title: Innovations of Wen-Shen Chu in Prolyl Oligopeptidase Activity
Introduction
Wen-Shen Chu is a notable inventor based in Hsinchu, Taiwan. He has made significant contributions to the field of biochemistry, particularly in the development of proteins with prolyl oligopeptidase activity. With a total of 14 patents to his name, his work has implications for medical treatments, especially concerning celiac disease.
Latest Patents
Wen-Shen Chu's latest patents include innovative proteins that exhibit prolyl oligopeptidase activity. One of his notable inventions is a protein that is isolated and characterized by its amino acid sequences, specifically SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:9, and SEQ ID NO:10, which must show at least 60% similarity. This protein demonstrates improved heat stability and optimal activity conditions around 40 degrees centigrade and pH 7. It has potential applications in medicaments for treating celiac disease caused by proline-rich gluten. Another significant patent involves a protein with an amino acid sequence SEQ ID NO:6, which is stable at temperatures ranging from 30 to 37 degrees centigrade and has optimal prolyl oligopeptidase activity at approximately 45 degrees centigrade and pH 7. This invention also relates to a medicament for treating celiac disease.
Career Highlights
Wen-Shen Chu has worked with prominent organizations such as the Food Industry Research and Development Institute and the Food Industry Research and Development. His career is marked by a commitment to advancing the understanding and application of biochemistry in food science and medicine.
Collaborations
Wen-Shen Chu has collaborated with notable colleagues, including Chiou-Yen Wen and Shie-Jea Lin, who have contributed to his research endeavors.
Conclusion
Wen-Shen Chu's innovative work in the field of prolyl oligopeptidase activity has the potential to significantly impact the treatment of celiac disease and other applications. His contributions to biochemistry and collaboration with esteemed colleagues highlight his importance in the scientific community.
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