The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2011

Filed:

Oct. 19, 2009
Applicants:

Jen-tao Chen, Hsinchu, TW;

Mei-li Chao, Hsinchu, TW;

Wen-shen Chu, Hsinchu, TW;

Chiou-yen Wen, Hsinchu, TW;

Inventors:

Jen-Tao Chen, Hsinchu, TW;

Mei-Li Chao, Hsinchu, TW;

Wen-Shen Chu, Hsinchu, TW;

Chiou-Yen Wen, Hsinchu, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/48 (2006.01);
U.S. Cl.
CPC ...
Abstract

Proteins isolated fromhaving prolyl oligopeptidase activity, nucleic acids encoding the protein and methods for producing and using the protein, wherein SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:9 and SEQ ID NO:10 must be contained therein to at least 60% similarity. The proteins and nucleic acids have improved heat stability and perform more favorably in vivo having optimum activity conditions around 40 degrees centigrade and around pH 7, and can therefore be used in medicaments for the treatment of celiac disease caused by proline abundant gluten or other applications.


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