Company Filing History:
Years Active: 1994-2002
Title: Walter E. Manger: Innovator in Vaccine Development
Introduction
Walter E. Manger is a notable inventor based in Harleysville, Pennsylvania. He has made significant contributions to the field of vaccine development, holding two patents that enhance the stability and efficacy of vaccine formulations.
Latest Patents
Manger's latest patents include a process for making human papillomavirus virus-like particles with improved properties. This innovative process involves subjecting the virus-like particles (VLPs) to various maturation conditions, such as higher temperatures and exposure to soluble metals or thios-oxidation. The matured VLPs exhibit greater stability, making them suitable for vaccine formulations with increased shelf life and higher potency. Another patent focuses on converting lipid-containing bacterial capsular polysaccharides into lipid-free, endotoxin-free polysaccharides. This process involves solubilizing polysaccharide-containing powder derived from bacterial culture media, cleaving covalently bound fatty acids, and removing lipids and endotoxins.
Career Highlights
Walter E. Manger is currently employed at Merck & Company, Inc., where he continues to work on innovative solutions in vaccine technology. His expertise and dedication to research have positioned him as a valuable asset in the pharmaceutical industry.
Collaborations
Manger has collaborated with notable colleagues, including Ann L. Lee and Mark S. Rienstra, contributing to advancements in their respective fields.
Conclusion
Walter E. Manger's work in vaccine development exemplifies the impact of innovative thinking in the pharmaceutical industry. His patents not only enhance vaccine stability but also contribute to public health advancements.