Fleurus, Belgium

Vincent Dubois



Average Co-Inventor Count = 5.3

ph-index = 5

Forward Citations = 102(Granted Patents)


Company Filing History:


Years Active: 2007-2011

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6 patents (USPTO):Explore Patents

Title: Vincent Dubois: Innovator in Therapeutic Prodrug Development

Introduction

Vincent Dubois is a notable inventor based in Fleurus, Belgium. He has made significant contributions to the field of therapeutic agents, particularly in the development of prodrug compounds. With a total of 6 patents, Dubois has focused on innovative solutions that enhance the efficacy of cancer treatments.

Latest Patents

One of Dubois's latest patents is centered around enzyme-cleavable prodrug compounds. This invention involves a modified form of a therapeutic agent that includes an oligopeptide, a stabilizing group, and, optionally, a linker group. The prodrug is designed to be cleavable by the enzyme Thimet oligopeptidase (TOP). Additionally, methods for designing prodrugs utilizing TOP-cleavable sequences and methods for treating patients with these prodrugs are disclosed.

Another significant patent involves prodrugs activated by plasmin, which are also aimed at cancer chemotherapy. This product comprises a therapeutic agent, an oligopeptide with a plasmin peptide substrate, and a stabilizing group. The prodrug is cleavable by plasmin, and the patent outlines methods for making and using these prodrug compounds.

Career Highlights

Throughout his career, Vincent Dubois has worked with prominent companies in the pharmaceutical industry, including Medarex Inc. and Coulter Pharmaceutical, Inc. His work has been instrumental in advancing therapeutic strategies that leverage prodrug technology.

Collaborations

Vincent has collaborated with notable professionals in his field, including Andre Trouet and Sanjeev Gangwar. These collaborations have contributed to the development of innovative therapeutic solutions.

Conclusion

Vincent Dubois stands out as an inventor dedicated to improving cancer treatment through his innovative prodrug compounds. His contributions to the field are marked by a commitment to enhancing therapeutic efficacy and patient outcomes.

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