Company Filing History:
2 out of 580 
2 out of 164 
Years Active: 2022
Title: Vikram Sarpe: Innovator in Antibacterial Drug Development
Introduction
Vikram Sarpe is a notable inventor based in Detroit, MI (US), recognized for his contributions to the field of antibacterial drug development. He holds 2 patents that focus on innovative derivatives of aminoglycoside antibacterial drugs. His work aims to enhance the efficacy of these drugs against resistant bacterial infections.
Latest Patents
One of his latest patents involves apramycin derivatives. This invention relates to derivatives of apramycin-based aminoglycoside antibacterial drugs modified in positions C5 and/or C6 and O5 and/or O6. The modifications impart favorable properties regarding increased selectivity and retention of activity in the presence of resistance determinants of the AAC(3) class. The invention further relates to these compounds for use in the therapy of bacterial infections by systemic administration, especially in instances where the infection is caused by a pathogen comprising a resistance determinant of the AAC(3) class, particularly AAC(3)-IV. Another significant patent pertains to neomycin and paromomycin derivatives. This disclosure relates to derivatives of neamine-based aminoglycoside antibacterial drugs modified in position C6', C2′, and/or C5″. The modifications impart favorable properties regarding activity against ESKAPE pathogens, evasion of resistance traits, and increased selectivity, enabling systemic use of the compounds.
Career Highlights
Vikram Sarpe has worked with prestigious institutions such as Wayne State University and Universität Zürich. His experience in these organizations has contributed to his expertise in the field of antibacterial drug research and development.
Collaborations
Throughout his career, Vikram has collaborated with notable individuals, including David Crich and Amr Sonousi. These collaborations have further enriched his research and innovation in the field.
Conclusion
Vikram Sarpe's work in developing novel antibacterial drugs showcases his commitment to addressing the challenges posed by resistant bacterial infections. His innovative patents reflect significant advancements in the field of medicine.