Location History:
- Houston, TX (US) (2004)
- Birmingham, AL (US) (2001 - 2007)
Company Filing History:
Years Active: 2001-2007
Title: Innovations of Victor N Krasnykh
Introduction
Victor N Krasnykh is a prominent inventor based in Birmingham, AL (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of adenoviral vectors for therapeutic applications. With a total of five patents to his name, his work has the potential to impact cancer treatment and gene therapy.
Latest Patents
One of his latest patents is titled "Adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob." This invention provides means to modify the tropism of recombinant adenoviral vectors using genetic methods to alter the adenoviral fiber cell-binding protein. The recombinant adenovirus generated through this invention has a fiber gene modified in the HI loop domain, achieving novel tropism. Another significant patent is "Infectivity-enhanced conditionally-replicative adenovirus and uses thereof." This patent describes a modified adenovirus capable of overcoming the low level of coxsackie-adenovirus receptor (CAR) expression on tumor cells. The fiber protein of the adenovirus is modified to target tumor cells, and the replication of the modified adenovirus is limited to these cells due to mutations in E1a or E1b genes.
Career Highlights
Victor N Krasnykh is associated with the UAB Research Foundation, where he continues to advance his research in adenoviral vectors. His innovative work has garnered attention in the scientific community, contributing to the understanding and application of gene therapy techniques.
Collaborations
Throughout his career, Victor has collaborated with notable colleagues, including David T Curiel and Igor Dmitriev. These collaborations have further enhanced the impact of his research and innovations in the field.
Conclusion
Victor N Krasnykh is a distinguished inventor whose work in adenoviral vectors holds promise for future advancements in cancer treatment and gene therapy. His contributions continue to shape the landscape of biomedical research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.