Location History:
- Boston, MA (US) (2002 - 2019)
- Newton, MA (US) (2019)
- Cambridge, MA (US) (2015 - 2020)
Company Filing History:
10 out of 443 
9 out of 216 
2 out of 1,206 
Years Active: 2002-2020
Title: Victor E. Kotelianski: Innovator in RNA Therapeutics
Introduction
Victor E. Kotelianski, based in Boston, MA, has made significant contributions to the field of biotechnology, particularly in RNA therapeutics. With an impressive portfolio of 24 patents, he stands out as a leading inventor focused on innovative solutions for complex medical conditions.
Latest Patents
Among his latest inventions are groundbreaking patents that address liver fibrosis and cholesterol regulation. One of his notable patents describes "Compositions and methods directed to treating liver fibrosis," which involves the use of double-stranded ribonucleic acid (dsRNA) compositions targeting specific genes including COL1A1, TGF-β, and SMAD2/3. This invention offers methods to inhibit the expression of these genes, paving the way for new treatments for liver fibrosis.
Another significant patent involves "Compositions and methods for inhibiting expression of the PCSK9 gene." This invention focuses on a dsRNA designed to inhibit the expression of the PCSK9 gene, with the antisense strand comprising a nucleotide sequence that is generally 19-25 nucleotides long and complementary to portions of the PCSK9 gene. The associated pharmaceutical composition can be utilized for treating diseases linked to PCSK9 gene expression.
Career Highlights
Throughout his career, Kotelianski has contributed his expertise to notable companies, including Alnylam Pharmaceuticals and Biogen Idec. His innovative work has positioned him at the forefront of developing RNA-based therapies that hold promise for a variety of medical conditions.
Collaborations
Victor has worked alongside distinguished scientists and experts in the field, including Antonin R. de Fougerolles and Carl Reid. These collaborations have enhanced his research and have played a pivotal role in furthering the development of RNA therapeutics.
Conclusion
Victor E. Kotelianski exemplifies the spirit of innovation in biotechnology. His extensive patent portfolio reflects his commitment to advancing medical science through the development of novel therapeutics. With his contributions, he continues to inspire future inventions and pave the way for breakthroughs in treating serious health conditions.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.