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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9944671 B1

PDFFull Text
Date of Patent:
Apr. 17, 2018

Filed:

Jun. 02, 2011

Compositions and methods directed to treating liver fibrosis

Applicants:

Greg Hinkle, Cambridge, MA (US);

Victor Kotelianski, Cambridge, MA (US);

Brian Bettencourt, Cambridge, MA (US);

Alfica Sehgal, Cambridge, MA (US);

Tatiana Novobrantseva, Cambridge, MA (US);

Inventors:

Greg Hinkle, Cambridge, MA (US);

Victor Kotelianski, Cambridge, MA (US);

Brian Bettencourt, Cambridge, MA (US);

Alfica Sehgal, Cambridge, MA (US);

Tatiana Novobrantseva, Cambridge, MA (US);

Assignee:

ALNYLAM PHARMACEUTICALS, INC., Cambridge, MA (US);

Attorneys:

Nixon Peabody LLP

Mark J. FitzGerald

Srividya Subramanian

Primary Examiner:

Jennifer Pitrak McDonald

Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); C07H 21/02 (2006.01); C07K 14/495 (2006.01); C07K 14/78 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07H 21/02 (2013.01); C07K 14/4705 (2013.01); C07K 14/495 (2013.01); C07K 14/78 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01);
Abstract

The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the COL1A1, TGF-β, and SMAD2/3 genes, and methods of using such dsRNA compositions to inhibit expression of COL1A1, TGF-β, and SMAD2/3.

Find Patent Forward Citations

Hinkle, Greg. (2018). Compositions and methods directed to treating liver fibrosis (U.S. Patent No. 9944671). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9944671

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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