Company Filing History:
14 out of 34 
2 out of 67 
1 out of 1 Years Active: 1988-2009
Title: **The Innovative Journey of Vernon L Alvarez: A Pioneer in Peptide Transport Technologies**
Introduction
Vernon L Alvarez, based in Morrisville, PA, is a distinguished inventor recognized for his significant contributions to the field of biomedical technology. With an impressive 17 patents to his name, Alvarez has focused much of his work on developing innovative methods for facilitating transport across human and animal tissues.
Latest Patents
Alvarez's recent work includes several groundbreaking patents related to peptides that enhance transport across tissues. One of his notable inventions is a method for identifying peptides that facilitate the transport of active agents through tissues. This method employs a predetermined amount of phage from a random or preselected phage library, administered in vivo or in situ, to evaluate which phage successfully traverses a tissue barrier. The process involves repeating cycles of amplification to obtain a selected phage library that contains phage capable of transport, ultimately identifying peptides that enable this crucial function.
Another significant patent pertains to random peptides that bind to gastrointestinal tract (GIT) transport receptors. This invention introduces proteins, including peptides, designed to help active agents cross through gastrointestinal tissues effectively. By binding these peptides to drugs administered orally, Alvarez's innovation helps target specific receptor sites or transport pathways in the human GIT, thereby enhancing the absorption of the drug into the systemic circulation.
Career Highlights
Throughout his professional career, Vernon Alvarez has made substantial contributions while working with renowned companies like Cytogen Corporation and Elan Corporation Plc. His research has positioned him as a key figure in the field of peptide technology and transport mechanisms, leading to practical applications in medicine and therapeutic delivery systems.
Collaborations
Over the years, Alvarez has collaborated with talented individuals such as Daniel J Coughlin and Benjamin A Belinka, Jr. These partnerships have facilitated the advancement of his research initiatives and significantly enriched the scientific community's understanding of peptide transport dynamics.
Conclusion
Vernon L Alvarez stands out as an innovative inventor whose work on peptides for tissue transport is paving the way for new therapeutic approaches. His impressive portfolio of patents and collaboration with industry leaders highlight his commitment to advancing biomedical science, ultimately contributing to improved drug delivery systems and patient care.