The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 30, 1990
Filed:
Jun. 07, 1988
Applicant:
Inventors:
Daniel J Coughlin, Robbinsville, NJ (US);
Benjamin A Belinka, Kendal Park, NJ (US);
Vernon L Alvarez, Morrisville, PA (US);
Assignee:
Cytogen Corporation, , NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
564150 ; 564390 ; 424-11 ; 424 8591 ; 530391 ; 530405 ;
Abstract
Radiohalogenated compounds which are useful as intermediates for preparing radiohalogenated antibody conjugates in which the radiohalogenated compound is site specifically attached to an oxidized carbohydrate moiety of an antibody or antibody fragment are disclosed. Methods for making the compounds and the antibody conjugates as well as methods of use of the same are also disclosed In particular, phenolic hydrazide and phenolic amine compounds are disclosed.