Location History:
- Plainsboro, NJ (US) (1989 - 1992)
- Robbinsville, NJ (US) (1990 - 1997)
- Mullica Hill, NJ (US) (2017 - 2018)
- Paulsboro, NJ (US) (2018)
Company Filing History:
15 out of 34 
3 out of 837 
1 out of 56 
Years Active: 1989-2018
Title: The Innovative Contributions of Daniel J Coughlin
Introduction
Daniel J Coughlin is a prominent inventor based in Robbinsville, NJ (US), known for his significant contributions to the field of pharmaceuticals. With a total of 19 patents to his name, Coughlin has made remarkable advancements in drug purification and synthesis methods.
Latest Patents
One of Coughlin's latest patents is a method for the purification of decitabine. This innovative process involves mixing crude decitabine with a solvent, such as dimethylacetamide, to create a solution or suspension. The purification process includes adding an anti-solvent, like ethanol, to the mixture, followed by cooling and isolating the solid decitabine. The method aims to achieve a high purity ratio of the β-anomer to the α-anomer of decitabine, ideally at least about 99.9:0.1. Another notable patent involves processes for making alkylated arylpiperazine and alkylated arylpiperidine compounds, which include novel intermediates and methods for their synthesis.
Career Highlights
Coughlin has worked with several reputable companies throughout his career, including Cytogen Corporation and Johnson Matthey Public Limited Company. His work in these organizations has contributed to the development of innovative pharmaceutical solutions.
Collaborations
Coughlin has collaborated with notable colleagues such as Benjamin A Belinka, Jr and Vernon L Alvarez, further enhancing his contributions to the field.
Conclusion
Daniel J Coughlin's innovative work in drug purification and synthesis has made a significant impact in the pharmaceutical industry. His numerous patents reflect his dedication to advancing medical science and improving therapeutic options.