The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
May. 15, 1998
Vernon L. Alvarez, Morrisville, PA (US);
Daniel J. O'mahony, Dublin, IE;
Imelda J. Lambkin, Dublin, IE;
Catherine A. Patterson, Dublin, IE;
Judith Singleton, Rocky Hill, NJ (US);
Benjamin A. Belinka, Jr., Kendall Park, NJ (US);
John M. Carter, Trenton, NJ (US);
Gerard M. Cagney, Seattle, WA (US);
Vernon L. Alvarez, Morrisville, PA (US);
Daniel J. O'Mahony, Dublin, IE;
Imelda J. Lambkin, Dublin, IE;
Catherine A. Patterson, Dublin, IE;
Judith Singleton, Rocky Hill, NJ (US);
Benjamin A. Belinka, Jr., Kendall Park, NJ (US);
John M. Carter, Trenton, NJ (US);
Gerard M. Cagney, Seattle, WA (US);
Cytogen Corporation, Princeton, NJ (US);
Abstract
This invention relates to proteins (e.g., peptides) that are capable of facilitating transport of an active agent through a human or animal gastrointestinal tissue, and derivatives (e.g., fragments) and analogs thereof, and nucleotide sequences coding for said proteins and derivatives. The proteins of the invention have use in facilitating transport of active agents from the lumenal side of the GIT into the systemic blood system, and/or in targeting active agents to the GIT. Thus, for example, by binding (covalently or noncovalently) a protein of the invention to an orally administered drug, the drug can be targeted to specific receptor sites or transport pathways which are known to operate in the human gastrointestinal tract, thus facilitating its absorption into the systemic system.