Location History:
- Kikuchi-gun, JP (1999 - 2005)
- Kumamoto-ken, JP (2006 - 2008)
- Kumamoto, JP (2006 - 2011)
Company Filing History:
9 out of 114 
1 out of 1,586 
Years Active: 1999-2011
Title: The Innovative Contributions of Tomohiro Nakagaki
Introduction
Tomohiro Nakagaki is a prominent inventor based in Kumamoto, Japan. He has made significant contributions to the field of biochemistry, particularly in the study of von Willebrand factor and its associated proteases. With a total of 9 patents to his name, Nakagaki's work has the potential to impact medical treatments for various blood disorders.
Latest Patents
One of Nakagaki's latest inventions is a vWF-cleaving protease, which is designed to isolate and identify a specific cleaving protease that targets von Willebrand factor. This protease cleaves a bond between residues Tyr 842 and Met 843 of vWF and includes a polypeptide chain with a specific sequence. The identification of this protease opens avenues for replacement therapy for patients suffering from conditions like thrombotic thrombocytopenic purpura. Another notable patent involves the development of an antibody that selectively reacts with ADAMTS-13, which can be used in diagnostic applications and epitope analysis. This antibody is produced by immunizing warm-blooded animals with a polypeptide containing the ADAMTS-13 amino acid sequence.
Career Highlights
Throughout his career, Nakagaki has worked with esteemed organizations such as the Chemo-Sero-Therapeutic Research Institute and Teijin Limited. His research has focused on the biochemical mechanisms underlying blood disorders, contributing to advancements in therapeutic strategies.
Collaborations
Some of Nakagaki's notable coworkers include Kenji Soejima and Noriko Mimura. Their collaborative efforts have furthered the understanding of von Willebrand factor and its clinical implications.
Conclusion
Tomohiro Nakagaki's innovative work in the field of biochemistry has led to significant advancements in the understanding and treatment of blood disorders. His contributions continue to pave the way for future research and therapeutic developments.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.